SYGNIS BIOTECH

SYGNIS BIOTECH

Category: Content
Type: Blog Article

Generated 2 days ago

New blog articles detected

  • Contamination – How to find them with TruePure

    The intention of this post is to help you using our contamination finder TruePure to search in your sequences for contaminations which may prevent your successful analysis. What you need to use TruePure To use TruePure, you will need sequences. You can use those sequences which were directly given by the next generation sequencing machine...

SYGNIS BIOTECH

Category: Content
Type: Blog Article

Generated 3 weeks ago

New blog articles detected

  • TruePrime – Nature Communications paper published

    We are very proud to announce that the renowned scientific journal Nature Communications has published a paper on our TruePrime method for single cell whole genome amplification, titled “TruePrime is a novel method for whole-genome amplification from single cells based on TthPrimPol”. We hope that others can benefit from the knowledge shared by our expert team in this...

  • Contamination – What to keep in mind when doing NGS sequencing

    The intention of this post is to bring a certain problem up onto the surface which is often ignored or even unknown: Contamination in the sequences acquired from Next Generation Sequencing. Contamination due to handling of the samples before sequencing Of course, all of us know that a clean lab is top priority for good...

  • Liquid Biopsy

    “Liquid biopsy” is a term coined to describe diagnostic procedures done on nucleic acids in the blood or in other bodily fluids (e.g. urine or cerebrospinal fluid (CSF)) of patients. Dying cells release DNA from their fragmented genomes into the bloodstream. This “cell-free” DNA can be broadly divided into two groups: The smaller size fragments...

  • 5 Methods for Checking Single-Cell WGA Success and Genome Coverage before Sequencing

    Isolation of single-cells while retaining whole genome integrity is challenging, whether using fluorescence-activated cell sorting, microfluidics, laser-capture microdissection, micromanipulation, dilution, or other techniques. And whole genome amplification (WGA) can introduce amplification bias and artefacts due to the use of random primers in excess and/or PCR. Consequently single-cell WGA can ...

  • 5 easy tips for getting good bands with SDS-PAGE protein gels

    The aim of this short post is to provide a few easy tips that can help with getting consistently good bands when running homemade and precast SDS-PAGE protein gels. If you run protein gels you may already know some of these tips, but we hope you will find some useful information regardless.   Consider heating...

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